DUBs platform
Deubiquitinating enzymes (DUBs) are an emerging drug target class of~100 proteases that cleave ubiquitin from protein substrates to regulate many cellular processes.
Biortus has over 39 biologically active DUBs for Custom Assay Development and high throughput screening and 18 ready to use commercial assay kits for high throughput screening and validation currently.
-
GPCRs
-
Functional Assay
-
Functional Assay
Active Deubiquitinase enzymes
| USP1 | USP51 | USP2 | UCHL1 |
| USP3 | UCHL3 | USP5 | UCHL5 |
| USP7 | BAP1 | USP8 | OTUD1 |
| USP9X | YOD1 | USP10 | OTUD6A |
| USP15 | OTUD7B (Cezanne-1) |
USP16 | ZRANB1 |
| USP20 | VCPIP1 | USP21 | ATXN3L |
| USP25 | ATXN3 | USP28 | JOSD1 |
| USP30 | JOSD2 | USP32 | SENP2 |
| USP37 | SENP5 | USP40 | SENP6 |
| USP48 | SENP8 |
Target specific platforms
