Assays & Screening

— Biortus experienced drug discovery team provides a variety of screening options.

NanoDSF/Thermal Shift Assay (TSA)

Light Cycler 480: A high-throughput TSA/DSF platform

The LightCycler®480 System is a proven high-performance, medium-to high-throughput PCR platform that provides various methods for gene detection, gene expression analysis, genetic variation analysis, and array data validation.
Applications:

Buffer screening

Small molecule interaction test

Fragment screening

  • Small molecule interaction test

  • Fragment screening

Prometheus: Dye free thermo shift assay instrument

The Prometheus NT.Plex is a high-performance nanoDSF instrument that provides high-quality protein unfolding curves, melting temperatures (Tm).
Applications:

Buffer screening

Small molecule interaction test

Fragment screening

  • Buffer screening

  • Small Molecule Interaction Test

  • Membrane Protein