BP14944-02A-Biortus Biosciences Co. Ltd.

BP14944-02A

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Family ：

Ras

Catalog No. ：

BP14944-02A

Protein ：

KRas4B

UniProt ：

P01116

Organism ：

Homo sapiens

Expression system ：

E. coli

Tag ：

GST

Sequence ：

T2-K169, G13D

Inquiry ：

是

Symbol/Gene Name: KRAS

Alias: GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras

Uniprot: P01116

Background: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).

Construct: GST-TEV-GG-KRas4B(T2-K169) (G13D)

Expression Host: E. coli

Purity: 90%

Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Recombinant protein

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