BP18374-02A
Family :
Ras
Catalog No. :
BP18374-02A
Protein :
KRas4B
UniProt :
P01116
Organism :
Homo sapiens
Expression system :
E. coli
Tag :
GST
Sequence :
T2-K169, G12A
Inquiry :
是
Symbol/Gene Name: KRAS
Alias: GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras
Uniprot: P01116
Background: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).
Construct: GST-TEV-GG-KRas4B(T2-K169) (G12A)
Expression Host: E. coli
Purity: 90%
Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein