BP13160-13A-Biortus Biosciences Co. Ltd.

BP13160-13A

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Family ：

E3 ubiquitin-protein ligase

Catalog No. ：

BP13160-13A

Protein ：

DCAF15

UniProt ：

Q66K64

Organism ：

Homo sapiens

Expression system ：

Insect cell

Tag ：

His/Strep

Sequence ：

A2-L600

Inquiry ：

是

Symbol/Gene Name: DCAF15

Alias: DDB1- and CUL4-associated factor 15

Uniprot: Q66K64

Background: Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins (PubMed:16949367, PubMed:31452512). The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3 (PubMed:31452512). May play a role in the activation of antigen-presenting cells (APC) and their interaction with NK cells (PubMed:31452512).

Construct: 8His-StrepII-TEV-(GG)-DCAF15(A2-L600 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Recombinant protein

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