BP08537-01A-Biortus Biosciences Co. Ltd.

BP08537-01A

Order Inquiry

Family ：

E3 ubiquitin-protein ligase

Catalog No. ：

BP08537-01A

Protein ：

MDM4

UniProt ：

O15151

Organism ：

Homo sapiens

Expression system ：

E. coli

Tag ：

His

Sequence ：

T2-A490

Inquiry ：

是

Symbol/Gene Name: MDM4

Alias: Protein Mdm4,Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4

Uniprot: O15151

Background: Along with MDM2, contributes to TP53 regulation (PubMed:32300648). Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Construct: 6His-TEV-(GG)-MDM4(T2-A490 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Recombinant protein

Ordering Information

Technical Support