MicroED Service at Biortus Facilitates Drug Development
Microcrystal electron diffraction (MicroED) is a new crystal structure determination technique for small molecules. It obtains diffraction patterns of small molecule microcrystal from an electron microscope, and resolves the atomic-resolution structure (better than 1.0A) with the traditional crystallography approach. The emergence of MicroED technology has raised great interest within the pharmaceutical research and development community. This technology holds great prospects of identifying the crystal form of drug substance, determining the structure of a natural product, and analyzing impurity in CMC process.
2020
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09
High-Quality Full-Length LRRK2 Ready for Structure-Based Drug Discovery
Leucine-rich repeat kinase 2 (LRRK2) is implicated in the pathogenesis of Parkinson’s disease (PD), which is the second most common neurodegenerative movement disorder and affects 1–2% of all people above the age of 65. Unfortunately, there has been no effective cure for PD yet. LRRK2 is one of the most promising therapeutic targets for drug therapy in PD and several LRRK2 inhibitors are currently in clinical trials.
2020
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06
Biortus Offers Critical Proteins of SARS-CoV-2
Joining global efforts to fight SARS-CoV-2, Biortus is offering several products and services to both scientific and industrial communities to assist researchers in finding effective treatments agains
2020
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05
Biortus Participating in the Mechanistic Study of Remdesivir and Co-authoring the Science Article
As a CRO company, Biortus often contributes to drug discovery work behind the scenes. As an innovative company, Biortus also appears in high quality scientific articles from time to time. This time, B
2020
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05
Biortus Successfully Enters the “List of R&D Enterprises in Jiangsu Province Cultivated in 2019”
With the sound of the New Year’s bell still ringing, Biortus welcomes the exciting news from the Department of Science and Technology at Jiangsu Province. In the Department’s first launched R&D Enterp
2020
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01
Expertise from Biortus contributes in the new Science article
In the newly published Science article “Cryo-EM Structures of the Human Cation-Chloride Cotransporter KCC1”, research teams revealed the structure of human potassium chloride co-transporter KCC1, base
2019
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11
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