BP10589-01A

Family :

Protease and Enzyme

Catalog No. :

BP10589-01A

Protein :

ADH7

UniProt :

P40394

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

G14-F386

Inquiry :

Product Information

Symbol/Gene Name:  ADH7

Alias:  All-trans-retinol dehydrogenase [NAD(+)] ADH7,Alcohol dehydrogenase class 4 mu/sigma chain,Alcohol dehydrogenase class IV mu/sigma chain,Gastric alcohol dehydrogenase,Omega-hydroxydecanoate dehydrogenase ADH7,Retinol dehydrogenase

Uniprot: P40394

Background: Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives (PubMed:15369820, PubMed:16787387, PubMed:9600267). Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid (PubMed:15369820, PubMed:16787387, PubMed:9600267). In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives (PubMed:15369820, PubMed:16787387, PubMed:9600267). Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal (PubMed:15369820, PubMed:16787387). Catalyzes in the oxidative direction with higher efficiency (PubMed:16787387, PubMed:15369820). Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation (PubMed:9600267, PubMed:15369820, PubMed:16787387).

Construct: 6His-TEV-adh7(G14-F386 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles

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