BP07896-13A

Family :

ABC

Catalog No. :

BP07896-13A

Protein :

ABCA1

UniProt :

O95477

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

Flag,Strep II,8His

Sequence :

A2-V2261

Inquiry :

Symbol/Gene Name:  ABCA1 (ABC1, CERP)

Alias:  Phospholipid-transporting ATPase ABCA1

Uniprot: O95477

Background: Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP(PubMed:24097981). Thereby, participates in phospholipid transfer to apoliproteins to form nascent high density lipoproteins/HDLs (PubMed:14754908). Transports preferentially phosphatidylcholine over phosphatidylserine (PubMed:24097981). May play a similar role in the efflux of intracellular cholesterol to apoliproteins and the formation of nascent high density lipoproteins/HDLs (PubMed:10533863, PubMed:14754908, PubMed:24097981).

Construct: 8His-Strep II-TEV-(GG)-ABCA1(A2-V2261 end)-Flag

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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