BP14288-00A

Family :

Protease and Enzyme

Catalog No. :

BP14288-00A

Protein :

HPGDS

UniProt :

O60760

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His/Strep

Sequence :

M1-L199

Inquiry :

Symbol/Gene Name:  HPGDS

Alias:  Hematopoietic prostaglandin D synthase,H-PGDS,GST class-sigma,Glutathione S-transferase,Glutathione-dependent PGD synthase,Glutathione-requiring prostaglandin D synthase,Prostaglandin-H2 D-isomerase

Uniprot: O60760

Background: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.

Construct: 6His-StrepII-TEV-GG-HPGDS(M1-L199 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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