Family :

Protease and Enzyme

Catalog No. :


Protein :


UniProt :


Organism :

Escherichia coli

Expression system :

E. coli

Tag :


Sequence :


Inquiry :

Symbol/Gene Name:  patZ

Alias:  Peptidyl-lysine N-acetyltransferase PatZ,Protein lysine acetyltransferase

Uniprot: P76594

Background: Catalyzes the acetyl-CoA-dependent acetylation of lysine residues of a large number of target proteins. Acetylates RNase R in exponential phase cells and RNase II (PubMed:21981926, PubMed:22124017, PubMed:26847092). Required for the glucose-dependent acetylation on multiple lysines of alpha, beta and beta' RNAP subunits (PubMed:21696463). Also acetylates acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, and inhibits their activity (PubMed:22059728, PubMed:26251518, PubMed:27484197). Overexpression leads to the acetylation of a large number of additional proteins and inhibits motility (PubMed:30352934).

Construct: 6His-StrepII-TEV-GG-patZ(S2-S886 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.


< 0.01 EU per μg of the protein


Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.