BP11327-00A

Family :

PRRs

Catalog No. :

BP11327-00A

Protein :

Sox2

UniProt :

P48431

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

No tag

Sequence :

R40-D123

Inquiry :

Symbol/Gene Name:  SOX2

Alias:  Transcription factor SOX-2

Uniprot: P48431

Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Binds to the proximal enhancer region of NANOG (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency (PubMed:18035408). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). May function as a switch in neuronal development (By similarity).

Construct: GG-Sox2(R40-D123)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris (pH 7.5), 150 mM NaCl, 5% glycerol

Supplied as sterile.

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

MESSAGE

Submit
%{tishi_zhanwei}%