BP08434-15A

Family :

SLC

Catalog No. :

BP08434-15A

Protein :

SLC27A4

UniProt :

Q6P1M0

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

8His-MBP,Flag

Sequence :

L2-L643

Inquiry :

Symbol/Gene Name:  SLC27A4

Alias:  Long-chain fatty acid transport protein 4,FATP-4,Fatty acid transport protein 4,Arachidonate--CoA ligase,Long-chain-fatty-acid--CoA ligase,Solute carrier family 27 member 4,Very long-chain acyl-CoA synthetase 4,ACSVL4

Uniprot: Q6P1M0

Background: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane (PubMed:12556534, PubMed:21395585). Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs) (PubMed:24269233). Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity). Probably involved in fatty acid transport across the blood barrier (PubMed:21395585). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).

Construct: 8His-MBP-TEV-(GG)-SLC27A4(L2-L643)-Flag

Expression Host: Insect cell

Purity: 90%

Formulation:

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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