BP11158-12A

Family :

Kinase

Catalog No. :

BP11158-12A

Protein :

FIP1L1

UniProt :

Q6UN15

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

His/GST

Sequence :

S2-E594

Inquiry :

Product Information

Symbol/Gene Name:  FIP1L1

Alias:  Pre-mRNA 3'-end-processing factor FIP1,hFip1,FIP1-like 1 protein,Factor interacting with PAP,Rearranged in hypereosinophilia

Uniprot: Q6UN15

Background: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.

Construct: 8His-GST-TEV-GG-FIP1L1(S2-E594 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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