BP14521-13A

Family :

Epigenetic

Catalog No. :

BP14521-13A

Protein :

EIF5A

UniProt :

P63241

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His/Strep

Sequence :

M1-K154

Inquiry :

Product Information

Symbol/Gene Name:  EIF5A

Alias:  Eukaryotic translation initiation factor 5A-1,eIF-5A-1,eIF-5A1,Eukaryotic initiation factor 5A isoform 1,eIF-5A,Rev-binding factor,eIF-4D

Uniprot: P63241

Background: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Construct: 6His-strepII-TEV-GG-EIF5A(M1-K154 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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