BP09868-04A

Family :

PRRs

Catalog No. :

BP09868-04A

Protein :

PYHIN1

UniProt :

Q6K0P9

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

Flag

Sequence :

M1-P492

Inquiry :

Symbol/Gene Name:  PYHIN1

Alias:  Pyrin and HIN domain-containing protein 1,Interferon-inducible protein X

Uniprot: Q6K0P9

Background: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.

Construct: PYHIN1(M1-P492 end)-Flag

Expression Host: E.Coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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