BP07099-02A

Family :

Kinase

Catalog No. :

BP07099-02A

Protein :

PRKX

UniProt :

P51817

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

GST

Sequence :

M1-F358

Inquiry :

Symbol/Gene Name:  PRKX

Alias:  cAMP-dependent protein kinase catalytic subunit PRKX,PrKX,Protein kinase X,Protein kinase X-linked,Serine/threonine-protein kinase PRKX,Protein kinase PKX1

Uniprot: P51817

Background: Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.

Construct: GST-TEV-PRKX(M1-F358 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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