BP13963-04A

Family :

membrane protein

Catalog No. :

BP13963-04A

Protein :

PORCN

UniProt :

Q9H237

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

GFP-Flag

Sequence :

Inquire for more details

Inquiry :

Symbol/Gene Name:  PORCN

Alias:  Protein-serine O-palmitoleoyltransferase porcupine,Protein MG61

Uniprot: Q9H237

Background: Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.

Construct: PORCN(M1-G461 end) (remove 219-228aa)  (C187A, A194S, K231G, R232T, K233M, A234V)-TEV-GFP-Flag

Expression Host: Insect cell

Purity: 95%

Formulation:

Supplied as sterile 25 mM HEPES (pH 7.3), 300 mM NaCl, 4 mM DM, 0.1 mg/ml POPS.

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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