BP05809-01A

Family :

Kinase

Catalog No. :

BP05809-01A

Protein :

PKL12

UniProt :

O75716

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

I15-I305

Inquiry :

Symbol/Gene Name:  STK16

Alias:  Serine/threonine-protein kinase 16,Myristoylated and palmitoylated serine/threonine-protein kinase,MPSK,Protein kinase PKL12,TGF-beta-stimulated factor 1,TSF-1,Tyrosine-protein kinase STK16,hPSK

Uniprot: O75716

Background: Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.

Construct: 6His-TEV-PKL12(I15-I305 end) (H19R, W266R)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

 

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